الأربعاء، 19 سبتمبر 2012

Discover francs to the causes of autism

نشرت من طرف : toofy  |  في  2:05 م

Swiss researchers managed to reach to identify a defect in the function of neural circuits that cause autism, and that causes the disorder in brain development easily diagnosed in early childhood.

Was able researchers Peter Skevil and Caspar Vogt Institute Biozentrum, University of Basel, Switzerland to find a way to counteract these neurological changes, which will have a great impact in reaching for a cure for autism, which affects approximately 1% of the world's children.

Autism is a genetic disease that occurs as a result of brain development disorder, where patients suffer from symptoms repeat certain behaviors permanently with the inability to communicate with others and the weakness in the capacity of speech.

There are many mutations in more than 300 gene have been identified as a key risk factor for autism injury, and one of those genes Hu neuroligin-3, which plays a role in the formation of tangles that allows the neuron to pass electrical or chemical signal to another cell.

The loss of this gene or a mutation inhibits the transmission of nerve signals.

The researchers were able in this study to detect a defect in the way in which signals transmitted through the entanglements that change the flexibility and function of neural circuits.

These results are related negative increase the production of a certain type of nerve receptors known as the "glutamate receptor", which is responsible for organizing the transfer of signals between nerve cells.

The defect occurs in brain function and growth over time with growing these nerve receptors that inhibit adaptation of the process of transferring signals through entanglements during the learning process.
The important thing here is to enable scientists to explore the possibility of correcting this imbalance in the development of neural circuits in the brain.

And when re-activating the production of neuroligin-3 gene in mice has neurons by reducing the production of these receptors glutamate receptor to normal levels, which led to the disappearance of the formative imbalance in the brain that causes autism.

As a result of this can be done targeting these receptors in the development of new treatments to stop the autism of evolution but completely cured.

At the present time there is no cure for autism but the symptoms can be alleviated treatment which relies on improving behavior.

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